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Antifungal potentials of Glycosmis pentaphylla extractives

By: Tofazzal Hossain, Omar Ali Mondal, Nazrul Islam

Key Words: Glycosmis pentaphylla, Chloroform, Methanol, Petrolium ether and Acetone extract, antifungal activity.

IES-Vol10-No1-p12-20, February 2023.

Abstract

The fresh flower, leaves, root, stem bark and stem wood of Glycosmis pentaphylla extracts (CHCl3, CH3OH, petroleum ether and acetone) were tested for their antifungal potentials against six pathogenic fungi Fusarium vasinfectum, Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, Mucor  sp. and Candida  albicans at concentrations of 200 µg/disc along with a standard Nystatin (50 µg/disc). The flower and leaf extracts showed activity against F. vasinfectum, A. fumigatus, A. niger, C. albicans and Mucor sp. in case of CHCl3 extracts. The root, stem bark and stem wood extracts were responsive against A. fumigatus, A. niger, C. albicans and Mucor sp.The flower extracts (CH3OH) was responsiveagainst three pathogenic fungi A. fumigatus, A. nigerand, C. albicans. For the leaf extract, F. vasinfectum, A. fumigatus, A. niger, C. albicans and Mucor sp. were responsive. The root extracts showed activity against A. fumigatus, A. niger, C. albicans and Mucor sp. In case of the stem wood extract A. fumigatus, A. niger, A. flavus, C. albicans and Mucor sp. were responsive. For the stem bark extract A. fumigatus, A. niger, C. albicans and Mucor sp.showed activity. The flower and leaf extracts (petroleum-ether) were responsive against F. vasinfectum,  A.niger, and C. albicans. The root extracts showed activity against F. vasinfectum A. niger, C. albicans and Mucor sp.In case of the stem wood extract A. fumigatus, A. nigerand Mucor sp. were responsive. For the stem bark extract A. fumigatus, A. niger and C. albicans wereresponsive. The flower extracts (acetone)  were responsiveagainst F. vasinfectum, A. niger, C. albicansand Mucor sp. The leaf extracts was responsive against F. vasinfectum, C. albicans and Mucor sp. The root extracts showed activity against A. fumigatus, A. niger, C. albicans and Mucor sp. The stem wood extracts showed activity against A. fumigatus, A. flavus, C. albicans and Mucor sp.For the stem bark extract A. fumigatus, A. niger, C. albicans and Mucor sp. were responsive. According to the intensity of activity indices G. pentaphylla extracts (CHCl3) could be arranged in a descending order of leaf >root > stem wood > stem bark > flower extract. For the MeOH extracts root > stem bark > leaf >stem wood > flower extract. In case of petroleum-ether extracts stem wood > stem bark > root > leaf > flower extract. For the acetone extracts stem wood > stem bark >leaf >root > flower extract

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Tofazzal Hossain, Omar Ali Mondal, Nazrul Islam

Antifungal potentials of Glycosmis pentaphylla extractives

IES-Vol10-No1-p12-20, February 2023.

https://jenvosci.com/ies-publish/antifungal-potentials-of-glycosmis-pentaphylla-extractives/

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